HEALTH

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Title: The Silent Alarm
Author: Michael Tennesen                                                          
Source:  NATURAL HEALTH, July-August 2004 v35 i7 p48(5).
Data Base: InfoTrac Web

                                                                             
THE SILENT ALARM

by Michael Tennesen

(Your liver filters the fallout from a toxic world, but symptoms of disease 
can stay dormant for decades. Here, the diet, supplements and proactive 
approach you need to keep this vital organ strong and healthy.)

Europeans eat bitter foods, drink lemon juice, go to spas, and attribute 
everything (rightly or wrongly) to their livers from moods to queasy stomachs. 
Americans, however, seem to ignore it. That's because the liver is the silent 
organ. It doesn't have any nerve endings on the inside. Says says Caroline 
Riely, MD, associate medical director of the American Liver Foundation, "Even 
patients with cirrhosis often don't have any symptoms at all." 

Because you may not feel it doesn't make your liver any less important. It's 
the largest organ in the body and has critical duties. It neutralizes toxins 
in the blood, produces immune agents to fight infection, and filters germs 
and bacteria from the blood. It makes proteins that regulate blood clotting, 
produces bile to help absorb fats, and it stores glucose for when you need 
energy. "Without the liver you cannot live," says Leonard Seeff MD, a senior 
scientist for hepatitis research at the National Institute of Diabetes and 
Digestive and Kidney Disease, "It is the metabolic factory of the entire 
body."

Western physicians and alternative practitioners don't always agree over how 
to care for the liver. According to Dr. Riely, "It's not like a muscle; you 
can't make it better." But alternative practitioners like Frank Lipman MD 
author of Total Renewal, believes that in today's polluted environment you can 
assist the liver by decreasing the toxins you put into your body and improving 
the nutrients you give it.

Dr. Lipman advises his patients to eat organic as much as possible. "That way 
you can avoid pesticides and herbicides on vegetables and fruit and the 
hormones, steroids, and antibiotics that come with various animal proteins," 
says Lipman. He recommends water filtration.

He also encourages adding blueberries, cabbage, broccoli, Brussels sprouts, 
watercress, walnuts, and almonds to the diet since they contain liver 
detoxification properties. Spices like ginger, rosemary, and garlic are also 
good. 

Carolyn Dean, MD, ND, author of The Miracle of Magnesium and Natural 
Prescriptions for Common Ailments, says that the best foods for the liver 
tend to be the bitter foods. Things like artichokes, dandelion greens, beet 
tops, beets, chard, spinach, and arugula. She encourages patients to eat a 
lot of fruits, vegetables, and whole grains to get the proper vitamins and 
minerals. She also recommends green tea and saunas. 

At the top of her list of supplements for liver health is milk thistle. A 250 
to 300 mg supplement taken 2 to 3 times a day is "very safe and very 
effective." She says alpha lipoic acid, a powerful antioxidant, which helps 
support liver detoxification. She tells her patients to try 2 or 3 of these 
liver friendly things each day rather than a dozen. "If you get too obsessive 
about it, you'll just stop, and that defeats the purpose." 

Physicians warn against taking too many drugs, whether pharmaceutical, herbal, 
or over the counter medications. Acetaminophen (a common pain reliever) can 
become unusually toxic when mixed with alcohol. And acetaminophen is found in 
a number of medications including pharmaceutical painkillers as well as 
certain cold remedies. Read the label and don't exceed the recommended daily 
allowance even on vitamins.

What happens if you don't take care of your liver? For one, you can get 
cirrhosis. It's a scary word. But according to Dr. Riely, "Cirrhosis just 
means scarring, it is the end stage of a the progression of liver disease, 
but it is not necessarily a death threat." It is, however, the twelfth 
leading cause of death by disease, killing 26,000 people each year. It can 
also lead to liver cancer.

Chronic alcoholism is one of the big causes of cirrhosis. About 50% of those 
who drink too much get cirrhosis. Dr. Dean advises drinking no more than two 
alcoholic beverages a day for a man, one for a woman. 

Though alcoholism gets the most press, hepatitis is responsible for more 
cirrhosis. According to Dr. Seeff, hepatitis B is the most common cause of 
cirrhosis worldwide, but hepatitis C is the leading cause in the U.S.  
That's because both these forms of the disease can become chronic ailments, 
which may wear down the liver even 25, 30, or 40 years after they are 
contracted. 

Both hepatitis B and C can be acquired by the exchange of body fluids or 
blood from mother to infant or with an infected person during unprotected 
sex, or sharing needles or snorting cocaine, even, according to Dr. Seeff, 
"if you only did it once." 

Hepatitis can also be transmitted through improperly sterilized 
body-piercing and tattooing needles. The American Liver Foundation estimates 
that there may be as many as 4 million affected with Hepatitis C in the U.S. 
"The trouble is the vast majority of people affected with Hep B and C, but 
particularly Hep C have no symptoms at all," says Dr. Seeff. "So that many 
don't know they have the disease."

There are a number of other less common diseases: autoimmune hepatitis; 
several inherited diseases including Alpha-1 antitrypsin deficiency, Wilson's 
disease, and others. According to Dr. Riely, "Women have a greater variety of 
liver diseases, but men have more liver problems because a greater number of 
them have hepatitis and alcoholic liver disease."

An annual blood test may tell you how healthy your liver is. Elevated ALT or 
AST scores are an indication something is wrong. Your doctor may then test 
for specific diseases.

One of the most startling diseases now in our country is nonalcoholic 
steatohepatitis (NASH), which is related to the rise in obesity. As fat 
builds up in the liver it creates scar tissue. According to Dr. Seeff, "The 
number one cause of death in overweight people is liver disease." 

To manage weight, get plenty of exercise and watch your diet. According to 
Dr. Dean, the body is constantly regenerating itself. "Every seven years of 
so you have a new body. If you give it the right building blocks you can 
overcome incredible odds."

TEN GOOD THINGS YOU CAN DO FOR YOUR LIVER. 

1. Drink no more than one alcoholic beverage a day for a woman, two for a 
man. 

2. Avoid over medicating yourself.

3. Don't mix acetaminophen with alcohol. Don't exceed the maximum daily 
dosage.

4. Don't inject or inhale drugs.

5. Use condoms if you have multiple sex partners.

6. Insist that tattoo or piercing needles be sterilized.

7. Don't share toothbrushes or razors with others.

8. Avoid fatty foods.

9. Eat more fruits, vegetables, whole grains, and legumes.

10. Get regular exercise.

HERBS, BOTANICALS, AND FOODS

Milk thistle: The extract contains silymarin, a free radical fighter that 
optimizes liver function, and helps the liver counteract toxins and 
pollutants. It can interfere with some HIV medication. Ask you doctor.

Alpha-Lipoic Acid: a powerful antioxidant that supports liver function. It 
recycles antioxidants like vitamin C and E. It can interfere with some 
diabetes medication. Ask your doctor. 

Bitter herbs: Things like artichokes, dandelion greens, beat tops, chard, 
spinach, and arugula have an astringent quality that keeps bodily fluids 
moving through the liver and gall bladder.

Beverages: Green tea, ginger tea, chicory, warm lemonade, and dandelion root 
tea all have liver supporting properties.

HEPATITIS

There are 5 types of hepatitis: Hep A, B, C, D, and E. According to NIH 
hepatitis researcher Leonard Seeff MD, only A, B, and D are serious health 
risks in the U.S. 

HEPATITIS A: The virus is transmitted by eating foods containing 
contaminated fecal material. Its symptoms are flu-like but can include 
jaundice. There is no chronic or long term infection, but 15% of people 
infected will have re-occurring symptoms over 6-9 months. Hepatitis A 
vaccine or immune globulin can prevent the disease. 

HEPATITIS B: The disease is transmitted with the exchange of body fluids or 
blood from an infected person--unprotected sex, sharing needles, or from 
mother to infant. The symptoms are jaundice, fatigue, abdominal pain, loss 
of appetite, nausea, and joint pain. 30% of patients have no symptoms. The 
chronic infection rate is 90% at birth but decreases to 6% after age 5 years. 
Between 15-25% of chronic infections will die of the disease. Hepatitis B 
vaccine is the best protection. Avoid unprotected sex outside a monogamous 
relationship and illicit IV drug use. Adefovir dipivoxil, alpha interferon, 
and lamivudine are three drugs used to treat this disease.

Hepatitis C: Is transmitted by the exchange of body fluids or blood from an 
infected person--unprotected sex, sharing needles, or mother to infant. The 
symptoms include jaundice, fatigue, dark urine, abdominal pain, loss of 
appetite, nausea. 80% of persons have no signs of symptoms. Chronic infection 
occurs in 75% to 80% of infected persons and 1%-5% of infected persons may 
die from chronic liver disease. There is no vaccine for hepatitis C. 
Interferon and ribavirin are used to threat this disease.

THE COMEBACK KID: Though the liver is susceptible to toxins and disease it is 
nevertheless remarkably resilient. In living donor transplants where 
physicians take half the liver of the donor, it takes only three to six weeks 
for the donor's liver to completely regenerate. 

LIVER FAST, ANYONE? Carolyn Dean MD, ND cautions against liver fasts since 
starvation can release a flood of toxins stored up in fat cells and because 
it also deprives the body of protein which the liver needs to regenerate. 

HELPFUL WEB SITES: The American Liver Foundation's web site, 
www.liverfoundation.org, has basic information about the liver. The National 
Center for Infectious Diseases, www.cdc.gov, has descriptions of liver 
diseases. The National Institute of Diabetes and Digestive and Kidney 
Diseases, www.niddk.nih.gov, lists conventional treatment options for liver 
disease. The American Botanical Council, www.herbalgram.org, can tell you 
about beneficial herbs. The web site for Environmental Working Group, 
www.ewg.org, lists fruits, vegetables, and other food products that contain 
pesticides or dangerous chemicals like mercury. 


MILK THISTLE (sidebar) 

The gold standard of liver protective herbs, according to Carolyn Dean MD, 
ND, is milk thistle. She advises patients to take 200 to 300 mg capsules, 
2 to 3 times a day. "It is very, very safe."

German scientists were the first to isolate a mixture of chemicals from the 
milk thistle fruit, which they named sylymarin. It is sold in Germany as a 
supportive treatment for chronic liver disease. (It can, however, interfere 
with some HIV medication.)

That's not to say that if you overindulge regularly that taking milk 
thistle will prevent liver damage. But once you've stopped drinking, it may 
help you recover from the abuse. Milk thistle may also help reduce liver 
enzyme scores for hepatitis patients, though it won't irradiate the virus. 
Still, according to Dr. Seeff, hepatitis patients with lower enzyme scores 
have less a chance of advancing to cirrhosis. 

                                  -- The End --